Atelocollagen is produced by removing the telopeptide regions of collagen. This process reduces the material's immunogenicity, meaning it elicits fewer immune responses in the body. Atelocollagen is commonly used in medical devices and tissue engineering applications. In recent years, it has also found significant use in the cosmetics industry.

 

What is Atelocollagen?

Atelocollagen is a purified form of collagen obtained by enzymatically or chemically removing its telopeptide regions. Telopeptides are responsible for cross-linking between collagen molecules but are recognized as immunogenic by the immune system. Removing these regions significantly reduces the immunogenicity of atelocollagen, making it less likely to provoke an immune response and safer in terms of biocompatibility.

Medical Applications of Atelocollagen

Atelocollagen has a wide range of uses in the biomedical field. By combining the biocompatibility of natural collagen with its biomechanical properties, it plays a critical role in various treatment and repair processes. Key applications include:

  • Tissue Engineering:
    Atelocollagen serves as an ideal biomaterial for cell culture and tissue engineering. It acts as a scaffold supporting cell growth and plays a vital role in tissue regeneration.

  • Wound Healing:
    Collagen-based products are frequently preferred for wound healing. When used as a wound dressing material, atelocollagen promotes cell proliferation, accelerates healing, and reduces scar formation.

  • Aesthetic and Reconstructive Surgery:
    Atelocollagen can be used as a dermal and tissue filler. Its high biocompatibility makes it a preferred material for patients with a low risk of tissue incompatibility.

Cosmetic Applications of Atelocollagen

In recent years, atelocollagen has become a significant component in the cosmetics industry. Its structure, which enhances skin elasticity and supports moisture balance, has led to its frequent use in anti-aging products and skincare formulations. Atelocollagen helps boost collagen production in the skin, reducing wrinkles and fine lines. Additionally, it strengthens the skin’s barrier functions, offering better protection against external factors.

Molecular Structure and Biocompatibility

The biocompatibility of atelocollagen is ensured by preserving the structural integrity of natural collagen while removing its immunogenic regions. This feature allows for long-term use in medical and cosmetic applications. Its low immunogenicity results in minimal inflammatory response in the body, enabling prolonged biological compatibility and safe usage.

Atelocollagen stands out as a highly effective biomaterial in both medical and cosmetic fields. Its biocompatibility, low immunogenicity, and tissue-regenerating properties allow for extensive applications ranging from tissue engineering to cosmetic products. With advancing technologies, the scope of atelocollagen's applications is expected to expand further, unlocking new potential in biomedicine and skincare.

 

 

Atelocollagen products are listed below. These products provide effective solutions for a wide range of applications, from skincare to wound healing. Each product is manufactured to high-quality standards, leveraging the biocompatible and low-immunogenic properties of atelocollagen.

 

#C1718 BUGA-CoL Type I Atelocollagen from Bovine Tendon Lyophilized, BSE FreeMore Information
#C1702 BUGA-CoL Type I Atelocollagen Insoluble Fibrous Powder from Bovine Tendon, BSE FreeMore Information
#C1703 BUGA-CoL Succinated Type I Atelocollagen in Water Soluble, BSE FreeMore Information
#C1801 BUGA-CoL Type I Atelocollagen Solutions from Bovine Tendon, Sterile Filtrated, BSE FreeMore Information
#C1803 BUGA-CoL Type I Atelocollagen Solutions for Cell Culture (in PBS) Sterile Filtrated BSE Free 6mg/mlMore Information
#C1713 BUGA-CoL Type II Atelocollagen from Chicken Sternum, LyophilizedMore Information
#C1812 BUGA-CoL Type II Atelocollagen Solutions from Chicken Sternum, 1 mg/mlMore Information

 

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