BUGA-CoL Type II Atelocollagen from Chicken Sternum, Lyophilized
Product Info
BUGA-CoL Type II Atelocollagen from Chicken Sternum (BUGA-AteloCol-II) is derived from chicken sternum cartilage obtained from certified organizations that apply the Turkish Food Codex, food safety, and quality standards. BUGA-AteloCol-II is produced under GMP conditions and is subject to FDA-approved viral inactivation studies. The product is a water-soluble atelocollagen with medical-grade purity.
BUGA-AteloCol-II is Type II collagen with high bioavailability. Type II collagen is found in hyaline cartilage and the vitreous body of the eye. It supports the structure of joint cartilage, promoting joint flexibility, mobility, and repair. BUGA-AteloCol-II is prepared as a gel that provides a 3D matrix or surface coating. It is preferred in medical device designs to support cartilage and synovial tissue.
This product is suitable for R&D purposes and is available in user-friendly packaging, supplied in lyophilized sponge form.
• Artificial Cartilage Tissue Designs
• Artificial Synovial Fluid Designs
• 3D Surface Coatings
• 3D Collagen Sponges (Cell Culture)
• Antigen-Requiring Studies for Antibody Production
• Weigh the required amount of **BUGA-AteloCol-II** product according to the desired solution concentration.
• Prepare **0.5 M acetic acid** in the appropriate solution volume.
• Combine the weighed **BUGA-AteloCol-II** product with the solution and allow mixing until dissolved using a magnetic stirrer.
• Store the prepared product at **2-8 °C**.
Note: After preparing the solution, avoid rapid stirring, shaking, or vortexing as it may cause cross-linking in the product.
Product Technical Specifications
Appearance | Lyophilized white color |
Smell | No data available |
Extraction method | Enzymatic- Atelocollagen |
Solubility/Collagen concentration | 1, 3, 6 mg/ml (in 0.01 M HCl) |
Storage temperature | Store at -20 ºC. After solution, store at 2-8 ºC. |
Shelf life | 2 years from date of production |
Solution shelf life | After making it into solution, 3 months (at +4 ºC) |
Source (Animal type) | Chicken Sternum |
SDS PAGE (Determination of molecular weight and impurity) | α chains formed at the level of 100-135 kDa and β chains formed at the level of 245 kDa are seen. |
• Harris, R. B., Fonseca, F. L. A., Sharp, M. H., & Ottinger, C. R. (2022). Functional characterization of undenatured type II collagen supplements: Are they interchangeable? Journal of dietary supplements, 19(6), 717-732.
• Kumar, P., Bansal, P., Rajnish, R. K., Sharma, S., Dhillon, M. S., Patel, S., & Kumar, V. (2023). Efficacy of undenatured collagen in knee osteoarthritis: review of the literature with limited meta-analysis. American Journal of Translational Research, 15(9), 5545.
• Luo, C., Su, W., Song, Y., & Srivastava, S. (2022). Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double‐blind, placebo‐controlled trial. Journal of Experimental Orthopaedics, 9(1), 123.
• Wang, H. (2021). A review of the effects of collagen treatment in clinical studies. Polymers, 13(22), 3868.
• Yoshinari, O., Moriyama, H., & Shiojima, Y. (2015). An overview of a novel, water-soluble undenatured type II collagen (NEXT-II). Journal of the American College of Nutrition, 34(3), 255-262.
• Zhou, Y., Zhang, Y., Dai, H., Zhang, Y., & Fu, Y. (2024). The potential of undenatured type II collagen against arthritis: a review. Collagen and Leather, 6(1), 17.
